SML0517

Amlexanox

≥98% (HPLC)

• Synonyme(s) : 2-Amino-7-(1-methylethyl)-5-oxo-5H-[1]Benzopyrano[2,3-b]pyridine-3-carboxylic acid, AA 673, Amoxanox, CHX 3673
• Formule empirique (notation de Hill) : C₁₆H₁₄N₂O₄
• CAS Number: 68302-57-8
• Poids moléculaire : 298.29
• Numéro MDL: MFCD00864790
• Code UNSPSC : 12352200
• ID de substance PubChem : 329825526
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Essai: ≥98% (HPLC)
• Forme: powder
• Couleur: white to beige
• Solubilité: DMSO: 10 mg/mL at warmed, clear
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Chaîne SMILES: CC(C)c1ccc2Oc3nc(N)c(cc3C(=O)c2c1)C(O)=O
• InChI: 1S/C16H14N2O4/c1-7(2)8-3-4-12-9(5-8)13(19)10-6-11(16(20)21)14(17)18-15(10)22-12/h3-7H,1-2H3,(H2,17,18)(H,20,21)
• Clé InChI: SGRYPYWGNKJSDL-UHFFFAOYSA-N
• Informations sur le gène: human ... PDE4A(5141), PDE4B(5142), PDE4C(5143), PDE4D(5144)

Description

Description générale

Amlexanox is an anti-allergic drug with anti-inflammatory properties.

Actions biochimiques/physiologiques

Amlexanox elevates the amount of nonsense-containing mRNAs in treated cells and helps to generate full-length proteins effectively.

Amlexanox is an anti-allergy and anti-asthma drug that blocks histamine and leukotriene release from leukocytes and mast cells. Amlexanox has also been shown to inhibit cahaperone activity of Hsp90, and S100A13, which is involved in transport of proteins devoid of signal peptide sequences.

Amlexanox is an anti-allergy, anti-ulcer drug; S100A13 inhibitor.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302
• Conseils de prudence: P264 - P270 - P301 + P312 - P501
• Classification des risques: Acute Tox. 4 Oral
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable