SML0629

Mitochondrial Fusion Promoter M1

≥95% (HPLC)

• Synonyme(s) : (E)-4-Chloro-2-(1-(2-(2,4,6-trichlorophenyl)hydrazono)ethyl)phenol, 1-(5-Chloro-2-hydroxyphenyl)-ethanone 2-(2,4,6-trichlorophenyl)hydrazone
• Formule empirique (notation de Hill) : C₁₄H₁₀Cl₄N₂O
• CAS Number: 219315-22-7
• Poids moléculaire : 364.05
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Essai: ≥95% (HPLC)
• Forme: powder
• Couleur: white to beige
• Solubilité: DMSO: 10 mg/mL, clear
• Température de stockage: 2-8°C
• Chaîne SMILES: Clc1c(c(cc(c1)Cl)Cl)NNC(=C)c2c(ccc(c2)Cl)O
• Clé InChI: WMAGOVJOXMBLHY-UHFFFAOYSA-N

Description

Application

Mitochondrial Fusion Promoter M1 has been used as a fusion promoter:

• to study its effects on peroxisome proliferator-activated receptor-γ coactivator (PGC)-1α expression in breast cancer cells
• to study the link between nucleoside diphosphate kinase 3 (NME3)-regulated mitochondrial fluctuations and stability of genome in NME3 knockdown cells
• to study its effects on mitochondrial fusion in neuronal cells

Actions biochimiques/physiologiques

Mitochondrial Fusion Promoter M1 is a cell permeable hydrazone that enhances mitochondrial fusion.

Mitochondrial Fusion Promoter M1 is a cell permeable hydrazone that enhances mitochondrial fusion. M1 protects cells from mitochondrial fragmentation associated cell death. Mitochondrial Fusion Promoter M1 does not interfere with endoplasmic reticula (ER) and lysosomes morphology.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable