SML1886

VPC-13566

≥98% (HPLC)

• Synonyme(s) : 2-(7-Methyl-1H-indol-3-yl)quinoline
• Formule empirique (notation de Hill) : C₁₈H₁₄N₂
• CAS Number: 218464-59-6
• Poids moléculaire : 258.32
• Code UNSPSC : 51111800
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Essai: ≥98% (HPLC)
• Forme: powder
• Couleur: white to beige
• Solubilité: DMSO: 20 mg/mL, clear
• Température de stockage: 2-8°C
• Chaîne SMILES: CC1=CC=CC2=C1NC=C2C3=NC4=CC=CC=C4C=C3
• Clé InChI: FPKBNOVQNMJTEJ-UHFFFAOYSA-N

Description

Actions biochimiques/physiologiques

VPC-13566 is Binding Function 3 (BF3)-specific inhibitor of the androgen receptor.

VPC-13566 is Binding Function 3 (BF3)-specific inhibitor of the androgen receptor. VPC-13566 potently inhibits AR transcriptional activity by displacement of the BAG1L peptide from the BF3 pocket. VPC-13566 inhibits the growth of various prostate cancer cell lines including an enzalutamide-resistant cell line and inhibits the growth of AR-dependent prostate cancer xenograft in mice.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable