SRP2073

N-CoR human

recombinant, expressed in insect cells, ≥60% (SDS-PAGE)

• Synonyme(s) : KIAA1047, MGC104216, N-CoR, N-CoR1, TRAC1, hN-CoR
• Code UNSPSC : 12352202
• Nomenclature NACRES : NA.24

Propriétés

• Source biologique: human
• Produit recombinant: expressed in insect cells
• Essai: ≥60% (SDS-PAGE)
• Forme: frozen liquid
• Poids mol.: ~271 kDa
• Conditionnement: pkg of 5 μg
• Concentration: 700 μg/mL
• Technique(s): deacetylase assay: suitable
• Couleur: clear colorless
• Numéro d'accès NCBI: NM_006311
• Numéro d'accès UniProt: O75376
• Conditions d'expédition: dry ice
• Température de stockage: −70°C
• Informations sur le gène: human ... NCOR1(9611)

Description

Actions biochimiques/physiologiques

This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined

Forme physique

Clear and colorless frozen liquid solution

Notes préparatoires

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable