T3251

(±)-α-Tocophérol

synthetic, ≥96% (HPLC)

• Synonyme(s) : DL-tout-rac-α-Tocophérol, Vitamine E
• Formule empirique (notation de Hill) : C₂₉H₅₀O₂
• CAS Number: 10191-41-0
• Poids moléculaire : 430.71
• Beilstein: 94012
• Numéro CE : 233-466-0
• Numéro MDL: MFCD00006848
• Code UNSPSC : 12352205
• eCl@ss : 34058016
• ID de substance PubChem : 24900118
• Nomenclature NACRES : NA.77

Propriétés

• Source biologique: synthetic
• Niveau de qualité: 200
• Essai: ≥96% (HPLC)
• Forme: liquid
• Technique(s): HPLC: suitable
• Couleur: faint brown to brown; yellow to very dark yellow
• Solubilité: H₂O: insoluble; acetone: miscible; chloroform: miscible; ethanol: miscible; vegetable oils: miscible
• Densité: 0.950 g/mL at 20 °C (lit.)
• Température de stockage: 2-8°C
• Chaîne SMILES: CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(O)c(C)c(C)c2O1
• InChI: 1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3
• Clé InChI: GVJHHUAWPYXKBD-UHFFFAOYSA-N

Description

Application

(±)-α-Tocopherol has been used for preparing mycobacterial emulsions. It has also been used to study its immunomodulatory effect on influenza virus.

Actions biochimiques/physiologiques

Tocopherols (vitamin E) comprise of a series (α, β, γ and δ) of chiral compounds that differ by the methylation degree of the phenol moiety of the chromanol ring. They function as lipid soluble antioxidants and protect cell membranes from oxidative damage. α-tocopherols are favorably absorbed by humans and their nicotinate salts can function as vitamin E supplements. Studies have also reported that vitamin E can prevent cell damage caused by pharmacologically induced epilepsy in rats.

Notes préparatoires

(±)-α-Tocopherol is miscible with chloroform, ethanol, ether, acetone, and vegetable oils. However, it is practically insoluble in water. (±)-α-Tocopherol is unstable under alkaline conditions.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H317
• Conseils de prudence: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Classification des risques: Skin Sens. 1
• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Équipement de protection individuelle: Eyeshields, Gloves