T5330

Tanshinone I

≥98% (HPLC)

• Synonyme(s) : Tanshinon I, Tanshinone A, Tanshinquinone I
• Formule empirique (notation de Hill) : C₁₈H₁₂O₃
• CAS Number: 568-73-0
• Poids moléculaire : 276.29
• Numéro MDL: MFCD00210563
• Code UNSPSC : 12352205
• ID de substance PubChem : 329826820
• Nomenclature NACRES : NA.25

Propriétés

• Niveau de qualité: 200
• Essai: ≥98% (HPLC)
• Forme: powder
• Couleur: red
• Solubilité: DMSO: 1 mg/mL
• Application(s): metabolomics; vitamins, nutraceuticals, and natural products
• Température de stockage: 2-8°C
• Chaîne SMILES: Cc1coc2-c3ccc4c(C)cccc4c3C(=O)C(=O)c12
• InChI: 1S/C18H12O3/c1-9-4-3-5-12-11(9)6-7-13-15(12)17(20)16(19)14-10(2)8-21-18(13)14/h3-8H,1-2H3
• Clé InChI: AIGAZQPHXLWMOJ-UHFFFAOYSA-N

Description

Description générale

Tanshinone I (Tan I) is a phenolic compound primarily isolated from Danshen. It has an abietane diterpene norditerpenoid o-quinones structure. Tan I have poor water solubility.

Application

Tanshinone 1 has been used:

• to test its hematopoiesis effects on human leukemia cell lines and zebrafish xenograft models
• to study its anti-cancer effects on two breast cancer cell lines (MCF7 and MDA-MB-23)
• as a reference standard to quantify the bioactive component S. miltiorrhiza extract (SME) using high-performance liquid chromatography (HPLC)

Actions biochimiques/physiologiques

Phenanthrenequinone constituent of Chinese medicinal herb Danshen (Salvia miltiorrhiza). Modulates or prevents breast cancer metastasis by regulating adhesion molecules. Anti-inflammatory.

Phenanthrenequinone constituent of Chinese medicinal herb Danshen (Salvia miltiorrhiza). Modulates or prevents breast cancer metastasis by regulating adhesion molecules.Anti-inflammatory.

TanshinoneI is extensively studied for its anticancer properties, it was reported to inhibit cancer cell invasion, metastasis, and migration and is a potent antitumor agent. It also displays antibacterial, neuroprotective, memory-enhancing, and cardioprotective activities.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable