T5699

m-3M3FBS

>97% (HPLC)

• Synonyme(s) : 2,4,6-Trimethyl-N-(3-trifluoromethyl-phenyl)-benzenesulfonamide, N-(3-Trifluoromethylphenyl)-2,4,6-trimethylbenzenesulfonamide
• Formule empirique (notation de Hill) : C₁₆H₁₆F₃NO₂S
• CAS Number: 200933-14-8
• Poids moléculaire : 343.36
• Numéro MDL: MFCD00095824
• Code UNSPSC : 41106300
• ID de substance PubChem : 329826829
• Nomenclature NACRES : NA.77

Propriétés

• Essai: >97% (HPLC)
• Forme: powder
• Couleur: white
• Pf: 114-114.8 °C (lit.)
• Solubilité: DMSO: >20 mg/mL
• Chaîne SMILES: Cc1cc(C)c(c(C)c1)S(=O)(=O)Nc2cccc(c2)C(F)(F)F
• InChI: 1S/C16H16F3NO2S/c1-10-7-11(2)15(12(3)8-10)23(21,22)20-14-6-4-5-13(9-14)16(17,18)19/h4-9,20H,1-3H3
• Clé InChI: ZIIUUSVHCHPIQD-UHFFFAOYSA-N

Description

Application

m-3M3FBS has been used for MAP kinase assay in 293T cells. It has also been used for intracellular calcium analysis¹. Furthermore, it has been used (at a conc. of 1 μM) as a PLC activator for sensitizing TRPA1 in HEK293t cells².

Actions biochimiques/physiologiques

First known direct activator of phospholipase C (activates β2, β3, γ1, γ2, δ1 isoforms).

Notes préparatoires

m-3M3FBS is soluble in DMSO at a concentration that is greater than 20 mg/ml.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)