T7508

Tetracaine hydrochloride

≥99%

• Synonyme(s) : 4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester, Amethocaine hydrochloride
• Formule empirique (notation de Hill) : C₁₅H₂₄N₂O₂ · HCl
• CAS Number: 136-47-0
• Poids moléculaire : 300.82
• Numéro MDL: MFCD00038912
• Code UNSPSC : 12352200
• ID de substance PubChem : 57654697
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 200
• Essai: ≥99%
• Solubilité: chloroform: soluble 30 parts; alcohol: soluble 40 parts; H₂O: soluble mg/mL; acetone: insoluble; benzene: insoluble; diethyl ether: insoluble
• Chaîne SMILES: Cl.CCCCNc1ccc(cc1)C(=O)OCCN(C)C
• InChI: 1S/C15H24N2O2.ClH/c1-4-5-10-16-14-8-6-13(7-9-14)15(18)19-12-11-17(2)3;/h6-9,16H,4-5,10-12H2,1-3H3;1H
• Clé InChI: PPWHTZKZQNXVAE-UHFFFAOYSA-N
• Informations sur le gène: human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

Description

Application

Tetracaine hydrochloride has been used for studying the pharmacological effects of spinal anesthesia. Tetracaine hydrochloride has also been used as a component of protease digestion buffers.

Topical ophthalmic anesthetic; used for spinal anesthesia

Actions biochimiques/physiologiques

Blocks voltage-sensitive release of Ca²⁺ from sarcoplasmic reticulum.

Caractéristiques et avantages

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Notes préparatoires

Tetracaine hydrochloride dissolves in water at 50 mg/ml to yield a clear, colorless solution. It is also soluble in 40 parts alcohol and 30 parts chloroform. However, it is practically insoluble in ether benzene or acetone.

Informations sur la sécurité

• Pictogrammes: GHS06
• Mention d'avertissement: Danger
• Mentions de danger: H301,H319,H336
• Conseils de prudence: P261 - P264 - P271 - P280 - P301 + P310 - P305 + P351 + P338
• Classification des risques: Acute Tox. 3 Oral - Eye Irrit. 2 - STOT SE 3
• Organes cibles: Central nervous system
• Code de la classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable