T8019

Tentoxin from Alternaria tenuis

Naturally occurring phytotoxic cyclic tetrapeptide

• Formule empirique (notation de Hill) : C₂₂H₃₀N₄O₄
• CAS Number: 28540-82-1
• Poids moléculaire : 414.50
• Numéro MDL: MFCD00133844
• Code UNSPSC : 12352200
• ID de substance PubChem : 24900492
• Nomenclature NACRES : NA.56

Propriétés

• Source biologique: fungus (Alternaria tenuis)
• Niveau de qualité: 200
• Essai: ≥95% (HPLC)
• Température de stockage: 2-8°C
• Chaîne SMILES: CC(C)CC1NC(=O)C(C)N(C)C(=O)CNC(=O)\C(=C/c2ccccc2)N(C)C1=O
• InChI: 1S/C22H30N4O4/c1-14(2)11-17-22(30)26(5)18(12-16-9-7-6-8-10-16)21(29)23-13-19(27)25(4)15(3)20(28)24-17/h6-10,12,14-15,17H,11,13H2,1-5H3,(H,23,29)(H,24,28)/b18-12-/t15-,17-/m0/s1
• Clé InChI: SIIRBDOFKDACOK-LFXZBHHUSA-N

Description

Description générale

Tentoxin is a majorly occurring cyclic tetrapeptide mycotoxin that is excreted by the Alternaria fungal species like Alternaria alternata and Alternaria tenuis.

Actions biochimiques/physiologiques

It induces chlorosis in germinating seedlings of many dicotyledonous plants. Tentoxin has been postulated to inhibit cyclic photophosphorylation by acting as an energy transfer inhibitor at the terminal steps of ATP synthesis and to target the F1 moiety of photosynthetic H⁺-ATPases. A kinetic analysis of the action of tentoxin on the chloroplast F1 H⁺-ATPase (CF1) portion of chloroplast ATP synthase has been reported.

Tentoxin is phytotoxic, which induces chlorosis in plant leaves and germinating seedlings. It also halts photophosphorylation by inhibiting chloroplastic ATP synthase. Tentoxin over energizes thylakoids and is converted to isotentoxin by UV irradiation.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)