T9778

Tropicamide

solid

• Synonyme(s) : N-Ethyl-2-phenyl-N-(4-pyridylmethyl)hydracrylamide, Ro 1-7683
• Formule empirique (notation de Hill) : C₁₇H₂₀N₂O₂
• CAS Number: 1508-75-4
• Poids moléculaire : 284.35
• Numéro CE : 216-140-2
• Numéro MDL: MFCD00058580
• Code UNSPSC : 12352200
• ID de substance PubChem : 24277879
• Nomenclature NACRES : NA.77

Propriétés

• Forme: solid
• Niveau de qualité: 100
• Couleur: white
• Solubilité: 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 4.3 mg/mL; ethanol: 5.6 mg/mL; H₂O: insoluble
• Température de stockage: 2-8°C
• Chaîne SMILES: CCN(Cc1ccncc1)C(=O)C(CO)c2ccccc2
• InChI: 1S/C17H20N2O2/c1-2-19(12-14-8-10-18-11-9-14)17(21)16(13-20)15-6-4-3-5-7-15/h3-11,16,20H,2,12-13H2,1H3
• Clé InChI: BGDKAVGWHJFAGW-UHFFFAOYSA-N
• Informations sur le gène: human ... CHRM3(1131), CHRM4(1132)

Description

Application

Tropicamide has been used for studying the regulation of fragile X behavior in male mice. 1% tropicamide has also been used for dilating mice pupils.

Actions biochimiques/physiologiques

M₄ muscarinic acetylcholine receptor antagonist.

Caractéristiques et avantages

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This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Conditionnement

Bottomless glass bottle. Contents are inside inserted fused cone.

Notes préparatoires

Tropicamide is soluble in 45% (w/v) aqueous 2-hydroxypropyl-beta-cyclodextrin (4.3 mg/mL) and ethanol (5.6 mg/mL).

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302 + H312 + H332,H315,H317,H319,H335
• Conseils de prudence: P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Classification des risques: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable