U1008

Urocortin III human

≥97% (HPLC)

• Formule empirique (notation de Hill) : C₁₈₅H₃₀₇N₅₃O₅₀S₂
• CAS Number: 351999-19-4
• Poids moléculaire : 4137.87
• Numéro MDL: MFCD03792654
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.32

Propriétés

• Source biologique: human
• Niveau de qualité: 200
• Essai: ≥97% (HPLC)
• Forme: solid
• Technique(s): ligand binding assay: suitable
• Numéro d'accès UniProt: Q969E3
• Température de stockage: −20°C
• Informations sur le gène: human ... UCN3(114131)

Description

Amino Acid Sequence

Phe-Thr-Leu-Ser-Leu-Asp-Val-Pro-Thr-Asn-Ile-Met-Asn-Leu-Leu-Phe-Asn-Ile-Ala-Lys-Ala-Lys-Asn-Leu-Arg-Ala-Gln-Ala-Ala-Ala-Asn-Ala-His-Leu-Met-Ala-Gln-Ile-NH2

Application

Urocortin III human can be used as a test compound for studying the impacts of melanocortin agonist on in vitro α-subunit secretion.

Actions biochimiques/physiologiques

Selective ligand with high affinity for CRF2 Receptors

Urocortin III belongs to corticotropin-releasing hormone family with high affinity for the type 2 corticotropin-releasing factor (CRFR2) receptor. It stimulates insulin and glucagon secretion.Urocortin III also possesses cardioprotective property and has minimal impact on the hypothalamic stress axis. It is, therefore, utilized for treating ischemic heart disease.

Autres remarques

Lyophilized from 0.1% TFA in H2O

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable