U6628

Uvaol

≥95%

• Synonyme(s) : Urs-12-ene-3,28-diol
• Formule empirique (notation de Hill) : C₃₀H₅₀O₂
• CAS Number: 545-46-0
• Poids moléculaire : 442.72
• Numéro CE : 208-888-3
• Numéro MDL: MFCD00009620
• Code UNSPSC : 12352103
• ID de substance PubChem : 24900437
• Nomenclature NACRES : NA.25

Propriétés

• Niveau de qualité: 100
• Essai: ≥95%
• Pf: 223-225 °C (lit.)
• Application(s): metabolomics; vitamins, nutraceuticals, and natural products
• Chaîne SMILES: C[C@@H]1CC[C@]2(CO)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2[C@H]1C
• InChI: 1S/C30H50O2/c1-19-10-15-30(18-31)17-16-28(6)21(25(30)20(19)2)8-9-23-27(5)13-12-24(32)26(3,4)22(27)11-14-29(23,28)7/h8,19-20,22-25,31-32H,9-18H2,1-7H3/t19-,20+,22+,23-,24+,25+,27+,28-,29-,30-/m1/s1
• Clé InChI: XUARCIYIVXVTAE-ZAPOICBTSA-N
• Informations sur le gène: mouse ... Nos2(18126)

Description

Description générale

Uvaolis a pentacyclic triterpene compound usually extracted from plant leaves such as Apocynum venetum L., olive leaves (Olea europaea L.), and oregano (Origanum vulgare L.).

Application

Uvaol has been used as retinoic acid receptor-related orphan receptor gamma t (RORγt) inhibitor to study the role of cardiac glycoside reductase 2 (Cgr2) enzyme on its metabolism.

Actions biochimiques/physiologiques

Uvaolexerts pharmacological properties such as antioxidant, anticancer, anti-inflammatory, and wound healing. It also displays vasodilator, hepatoprotective, and antimicrobial effects. Uvaol has inhibitory effects on nitric oxide (NO) release.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable