V1255

D-Valine

BioReagent, suitable for cell culture

• Synonyme(s) : (R)-α-Aminoisovaleric acid, D-2-Amino-3-methylbutanoic acid
• Formule linéaire : (CH₃)₂CHCH(NH₂)CO₂H
• CAS Number: 640-68-6
• Poids moléculaire : 117.15
• Beilstein: 1721135
• Numéro CE : 211-368-9
• Numéro MDL: MFCD00064219
• Code UNSPSC : 12352209
• ID de substance PubChem : 24900713
• Nomenclature NACRES : NA.75

Propriétés

• Source biologique: synthetic (organic)
• Gamme de produits: BioReagent
• Forme: powder
• Technique(s): cell culture | mammalian: suitable
• Pf: >295 °C (subl.) (lit.)
• Conditions d'expédition: ambient
• Température de stockage: room temp
• Chaîne SMILES: CC(C)[C@@H](N)C(O)=O
• InChI: 1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m1/s1
• Clé InChI: KZSNJWFQEVHDMF-SCSAIBSYSA-N

Description

Description générale

L-Valine is an essential non-polar amino acid. D-Valine is the non-proteinogenic isomer of valine.

Application

D-Valine has been used as a supplement in:

• Dulbecco′s modified Eagle′s medium (DMEM)/Nutrient Mixture F-12 Ham (F-12) for mice renal proximal tubule cell (RPTC) culture
• endothelial cell growth medium MV2 for rat lung microvascular endothelial cell (RLMEC) culture
• DMEM/F-12 for mouse tracheal epithelial cell (MTEC) culture

Actions biochimiques/physiologiques

D-Valine has a broad range of industrial applications such as semi-synthetic veterinary antibiotics, pharmaceutical drugs, and agricultural pesticides.

D-valine is used in cell culture as a selective inhibitor of cell proliferation, wherein it inhibits cells that lack the enzyme D-amino acid oxidase. Historically D-valine has been used to inhibit fibroblast growth while allowing selective growth of epithelial cells.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)