1082708

2,6-Di-tert-butyl-4-methylphenol

United States Pharmacopeia (USP) Reference Standard

• Synonyme(s) : Butylhydroxytoluène, Hydroxytoluène butylé
• Formule linéaire : [(CH₃)₃C]₂C₆H₂(CH₃)OH
• CAS Number: 128-37-0
• Poids moléculaire : 220.35
• Beilstein: 1911640
• Numéro CE : 204-881-4
• Numéro MDL: MFCD00011644
• Code UNSPSC : 41116107
• ID de substance PubChem : 329749182
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: pharmaceutical primary standard
• Densité de vapeur: 7.6 (vs air)
• Pression de vapeur: <0.01 mmHg ( 20 °C)
• Famille d'API: butylated hydroxytoluene
• Forme: crystalline powder
• Température d'inflammation spontanée: 878 °F
• Fabricant/nom de marque: USP
• pb: 265 °C (lit.)
• Pf: 69-73 °C (lit.)
• Application(s): pharmaceutical (small molecule)
• Format: neat
• Chaîne SMILES: Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C
• InChI: 1S/C15H24O/c1-10-8-11(14(2,3)4)13(16)12(9-10)15(5,6)7/h8-9,16H,1-7H3
• Clé InChI: NLZUEZXRPGMBCV-UHFFFAOYSA-N

Description

Description générale

Butylated hydroxytoluene (BHT) is a synthetic antioxidant commonly used in biologic formulations to prevent oxidative degradation. It acts as a preservative, protecting biologic products from oxidation, which can affect the potency and stability of sensitive molecules. Its application is critical in maintaining the integrity of biologics, particularly those that are exposed to air or light during production and storage.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Butylated hydroxytoluene USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Dutasteride and Tamsulosin Hydrochloride Capsules

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

This product is part of USP Biologics Program.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Ph

Sales restrictions may apply.

Informations sur la sécurité

• Pictogrammes: GHS09
• Mention d'avertissement: Warning
• Mentions de danger: H410
• Conseils de prudence: P273 - P391 - P501
• Classification des risques: Aquatic Acute 1 - Aquatic Chronic 1
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): 260.6 °F - open cup
• Point d'éclair (°C): 127 °C - open cup