1356836

Lamivudine

United States Pharmacopeia (USP) Reference Standard

• Synonyme(s) : 2′,3′-Dideoxy-3′-thiacytidine, 3TC, Epivir, Epivir-HBV, Heptovir, Zeffix
• Formule empirique (notation de Hill) : C₈H₁₁N₃O₃S
• CAS Number: 134678-17-4
• Poids moléculaire : 229.26
• Numéro MDL: MFCD00869739
• Code UNSPSC : 41116107
• ID de substance PubChem : 329750230
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: pharmaceutical primary standard
• Famille d'API: lamivudine
• Fabricant/nom de marque: USP
• Application(s): pharmaceutical (small molecule)
• Format: neat
• Chaîne SMILES: NC1=NC(=O)N(C=C1)[C@@H]2CS[C@H](CO)O2
• InChI: 1S/C8H11N3O3S/c9-5-1-2-11(8(13)10-5)6-4-15-7(3-12)14-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7+/m0/s1
• Clé InChI: JTEGQNOMFQHVDC-NKWVEPMBSA-N

Description

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Lamivudine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Abacavir and Lamivudine Tablets
• Abacavir, Lamivudine and Zidovudine Tablets
• Lamivudine
• Lamivudine and Zidovudine Tablets
• Lamivudine Oral Solution
• Lamivudine Tablets

Actions biochimiques/physiologiques

Lamivudine is a potent nucleoside analog reverse transcriptase inhibitor (nRTI).

Lamivudine is a potent nucleoside analog reverse transcriptase inhibitor (nRTI). It is an analogue of cytidine, and can inhibit both types (1 and 2) of HIV reverse transcriptase as well as the reverse transcriptase of hepatitis B. It needs to be phosphorylated to its triphosphate form before it is active. 3TC-triphosphate also inhibits cellular DNA polymerase.

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Informations sur la sécurité

• Pictogrammes: GHS08
• Mention d'avertissement: Warning
• Mentions de danger: H361
• Conseils de prudence: P280
• Classification des risques: Repr. 2
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable