1370280

Desloratadine

United States Pharmacopeia (USP) Reference Standard

• Synonyme(s) : 8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H- benzo[5,6]cyclohepta[1,2,b]pyridine, Clarinex^®
• Formule empirique (notation de Hill) : C₁₉H₁₉ClN₂
• CAS Number: 100643-71-8
• Poids moléculaire : 310.82
• Numéro MDL: MFCD00871949
• Code UNSPSC : 41116107
• ID de substance PubChem : 329750257
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: pharmaceutical primary standard
• Famille d'API: loratadine
• Fabricant/nom de marque: USP
• Application(s): pharmaceutical (small molecule)
• Format: neat
• Chaîne SMILES: Clc1ccc2c(CCc3cccnc3\C2=C4\CCNCC4)c1
• InChI: 1S/C19H19ClN2/c20-16-5-6-17-15(12-16)4-3-14-2-1-9-22-19(14)18(17)13-7-10-21-11-8-13/h1-2,5-6,9,12,21H,3-4,7-8,10-11H2
• Clé InChI: JAUOIFJMECXRGI-UHFFFAOYSA-N
• Informations sur le gène: human ... HRH1(3269)

Description

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Loratadine Related Compound A USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:

• Loratadine Orally Disintegrating Tablets
• Loratadine Chewable Tablets
• Loratadine Capsules

Actions biochimiques/physiologiques

A non-sedating H₁-receptor antagonist, free from antimuscarinic/anticholinergic effects. It has novel antiallergic and anti-inflammatory effects.

Desloratadine is a selective and nonsedating histamine H1 receptor antagonist, an active metabolite of loratadine (Claritin), used to relieve hay fever and allergy symptoms with less drowsiness than other antihistamines; does not significantly inhibits cardiac K+ channels at clinically achievable blood levels. Free from antimuscarinic/anticholinergic effects.

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Informations légales

Clarinex is a registered trademark of Schering Corp.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 390.2 °F - Pensky-Martens closed cup
• Point d'éclair (°C): 199 °C - Pensky-Martens closed cup