1615138
USP
Trifluoroacétate de sodium
United States Pharmacopeia (USP) Reference Standard
Synonyme(s) :
Trifluoroacétate de sodium, Acide trifluoroacétique sodium salt
About This Item
Produits recommandés
Qualité
pharmaceutical primary standard
Famille d'API
sodium trifluoroacetate
Forme
powder
Fabricant/nom de marque
USP
Pf
205-207 °C (dec.) (lit.)
Densité
1.49 g/mL (lit.)
Application(s)
pharmaceutical (small molecule)
Format
neat
Chaîne SMILES
[Na+].[O-]C(=O)C(F)(F)F
InChI
1S/C2HF3O2.Na/c3-2(4,5)1(6)7;/h(H,6,7);/q;+1/p-1
Clé InChI
UYCAUPASBSROMS-UHFFFAOYSA-M
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Description générale
Sodium trifluoroacetate (TFA) is a commonly encountered residual reagent or counter-ion in peptide synthesis and purification. It is often present due to the use of trifluoroacetic acid in cleavage and purification steps. The USP standard supports the identification and quantification of TFA in peptide active pharmaceutical ingredients (APIs) and formulations.
The USP biologics peptides category encompasses a diverse range of therapeutic peptides that are essential in managing various medical conditions. These peptides, typically consisting of amino acid sequences of 40 residues or less, are critical for the development of high-quality medicines. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of peptide therapeutics throughout their lifecycle.
The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.
Application
Also used to prepare trifluoroacetic acid (TFA) Stock solution to determine the amount of trifluoroacetic acid (TFA) in peptides according to the given below general chapter of United States Pharmacopeia (USP):
- 〈503.1〉 Trifluoroacetic acid (TFA) in peptides
Autres remarques
Mentions de danger
Conseils de prudence
Classification des risques
Aquatic Chronic 2
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
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