BP578

Dexametasona

British Pharmacopoeia (BP) Assay Standard

• Sinónimos: (11β,16α)-9-Fluoro-11,17,21-trihidroxi-16-metilpregna-1,4-dieno-3,20-diona, 9α-Fluoro-16α-metil-11β,17α,21-trihidroxi-1,4-pregnadieno-3,20-diona, 9α-fluoro-16α-metilprednisolona, Prednisolona F
• Fórmula empírica (notación de Hill): C₂₂H₂₉FO₅
• CAS Number: 50-02-2
• Peso molecular: 392.46
• Beilstein: 2066651
• Número CE: 200-003-9
• Número MDL: MFCD00064136
• Código UNSPSC: 41116107
• NACRES: NA.24

Propiedades

• grado: pharmaceutical primary standard
• familia API: dexamethasone
• Formulario: solid
• caducidad: limited shelf life, expiry date on the label
• fabricante / nombre comercial: BP
• mp: 262-264 °C (lit.)
• aplicaciones: pharmaceutical; pharmaceutical small molecule
• Formato: neat
• temp. de almacenamiento: 2-8°C
• cadena SMILES: C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
• InChI: 1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1
• Clave InChI: UREBDLICKHMUKA-CXSFZGCWSA-N
• Información sobre el gen: human ... NR3C1(2908)

Descripción

Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Dexamethasone BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Tobramycin and Dexamethasone Eye Drops, Suspension

Dexamethasone Sodium Phosphate Oral Solution

Hydrocortisone Sodium Succinate Injection

Prednisolone Tablets

Dexamethasone Eye Drops, Suspension

Dexamethasone Sodium Phosphate Eye Drops, Solution

Dexamethasone and Neomycin Ear Spray

Betamethasone Tablets

Dexamethasone Tablets

Acciones bioquímicas o fisiológicas

Glucocorticoide antiinflamatorio

Glucocorticoide antiinflamatorio. Regula la supervivencia, el crecimiento y la diferenciación de las células T. Inhibe la inducción de la óxido nítrico sintasa.

Otras notas

Sales restrictions may apply.

Información de seguridad

• Pictogramas: GHS08
• Palabra de señalización: Danger
• Frases de peligro: H360FD
• Consejos de prudencia: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Clasificaciones de peligro: Repr. 1B
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable