105902

p-Toluenesulfonamide

reagent grade, 97%

• Synonym(s): 4-Methylbenzene-1-sulfonamide, p-Tosylamide
• Linear Formula: CH₃C₆H₄SO₂NH₂
• CAS Number: 70-55-3
• Molecular Weight: 171.22
• Beilstein: 472689
• EC Number: 200-741-1
• MDL number: MFCD00011692
• UNSPSC Code: 12352100
• PubChem Substance ID: 24846713
• NACRES: NA.22

Properties

• grade: reagent grade
• Quality Level: 100
• Assay: 97%
• form: solid
• mp: 134-137 °C (lit.)
• solubility: DMSO: soluble
• functional group: sulfonamide
• SMILES string: Cc1ccc(cc1)S(N)(=O)=O
• InChI: 1S/C7H9NO2S/c1-6-2-4-7(5-3-6)11(8,9)10/h2-5H,1H3,(H2,8,9,10)
• InChI key: LMYRWZFENFIFIT-UHFFFAOYSA-N
• Gene Information: human ... CA1(759), CA2(760), CA5A(763), CA5B(11238)

Description

General description

p-Toluenesulfonamide undergoes FeCl₃-catalyzed direct substitution reaction with benzylic and allylic alcohols.It is employed as nucleophile in tetrabutylammonium fluoride (TBAF) catalyzed vinyl aziridine opening reaction.

Application

p-Toluenesulfonamide was used to prepare the precursor required for synthesis of ethyl 6-phenyl-1-tosyl-1,2,5,6-tetrahydropyridine-3-carboxylate.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): 395.6 °F - closed cup
• Flash Point(C): 202 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves