129712

Methyl 3-aminocrotonate

97%

• Synonym(s): Methyl 3-amino-2-butenoate
• Linear Formula: CH₃C(NH₂)=CHCOOCH₃
• CAS Number: 14205-39-1
• Molecular Weight: 115.13
• Beilstein: 956592
• EC Number: 238-056-5
• MDL number: MFCD00008072
• UNSPSC Code: 12352100
• PubChem Substance ID: 24847922
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: 97%
• form: solid
• mp: 81-83 °C (lit.)
• functional group: amine; ester
• SMILES string: COC(=O)\C=C(\C)N
• InChI: 1S/C5H9NO2/c1-4(6)3-5(7)8-2/h3H,6H2,1-2H3/b4-3+
• InChI key: XKORCTIIRYKLLG-ONEGZZNKSA-N

Description

General description

Methyl 3-aminocrotonate undergoes waste-free solid-state cascade reaction with crystalline ninhydrin.

Application

Methyl 3-aminocrotonate (Methyl 3-amino-2-butenoate) was used to synthesize 4-aryl-1,4-dihydropyridines possessing potential calcium channel blocking activity.

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H302,H317,H318
• Precautionary Statements: P261 - P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): 213.8 °F - closed cup
• Flash Point(C): 101 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves