186511

(S)-(+)-2-Pyrrolidinemethanol

97%

• Synonym(s): (S)-(+)-2-(Hydroxymethyl)pyrrolidine, L-Prolinol
• Empirical Formula (Hill Notation): C₅H₁₁NO
• CAS Number: 23356-96-9
• Molecular Weight: 101.15
• Beilstein: 79843
• EC Number: 245-605-2
• MDL number: MFCD00005255
• UNSPSC Code: 12352005
• PubChem Substance ID: 24851225
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 97%
• optical activity: [α]20/D +31°, c = 1 in toluene
• refractive index: n20/D 1.4853 (lit.)
• bp: 74-76 °C/2 mmHg (lit.)
• density: 1.025 g/mL at 25 °C (lit.)
• functional group: hydroxyl
• SMILES string: OC[C@@H]1CCCN1
• InChI: 1S/C5H11NO/c7-4-5-2-1-3-6-5/h5-7H,1-4H2/t5-/m0/s1
• InChI key: HVVNJUAVDAZWCB-YFKPBYRVSA-N

Description

General description

(S)-(+)-2-Pyrrolidinemethanol, also known as (S)-(+)-prolinol is a chiral building block that is used for the synthesis of chiral organic compounds. It is also used as a chiral auxiliary in asymmetric synthesis and a chiral ligand in asymmetric catalysis.

Application

(S)-(+)-2-Pyrrolidinemethanol can be used as a starting material for the synthesis of (S)-α, α-diaryl-2-pyrrolidinemethanols. It plays an important role in this synthesis by providing chirality to the final product.

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H302,H318,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P301 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): 186.8 °F - closed cup
• Flash Point(C): 86 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves