196894

4-(Trifluoromethyl)benzoic acid

98%

• Synonym(s): α,α,α-Trifluoro-p-toluic acid, 4-Carboxybenzotrifluoride
• Linear Formula: CF₃C₆H₄CO₂H
• CAS Number: 455-24-3
• Molecular Weight: 190.12
• Beilstein: 2049241
• EC Number: 207-242-8
• MDL number: MFCD00002562
• UNSPSC Code: 12352100
• PubChem Substance ID: 24851805
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 98%
• form: powder
• mp: 219-220 °C (lit.)
• functional group: carboxylic acid; fluoro
• SMILES string: OC(=O)c1ccc(cc1)C(F)(F)F
• InChI: 1S/C8H5F3O2/c9-8(10,11)6-3-1-5(2-4-6)7(12)13/h1-4H,(H,12,13)
• InChI key: SWKPKONEIZGROQ-UHFFFAOYSA-N

Description

Application

4-(Trifluoromethyl)benzoic acid was used in the synthesis of salicylanilide 4-(trifluoromethyl)benzoates via N,N′-dicyclohexylcarbodiimide coupling in dry N,N-dimethylformamide. It was used as internal standard during the ultra trace analysis of fluorinated aromatic carboxylic acids by GC/MS method.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves