269190

Methanesulfonic anhydride

97%

• Synonym(s): Mesyl anhydride, Mesylic anhydride, Methanesulfonyl anhydride, Methylsulfonyl methanesulfonate
• Linear Formula: (CH₃SO₂)₂O
• CAS Number: 7143-01-3
• Molecular Weight: 174.20
• Beilstein: 972316
• EC Number: 230-442-1
• MDL number: MFCD00007556
• UNSPSC Code: 12352100
• PubChem Substance ID: 24856315
• NACRES: NA.22

Properties

• vapor density: 3.3 (vs air)
• Quality Level: 200
• Assay: 97%
• form: solid
• bp: 125 °C/4 mmHg (lit.)
• mp: 64-67 °C (lit.)
• functional group: sulfonic acid
• SMILES string: CS(=O)(=O)OS(C)(=O)=O
• InChI: 1S/C2H6O5S2/c1-8(3,4)7-9(2,5)6/h1-2H3
• InChI key: IZDROVVXIHRYMH-UHFFFAOYSA-N

Description

General description

Methanesulfonic anhydride is an organic compound that is commonly used as a reagent for the preparation of methyl sulfonates (mesylates). It is also used in the synthesis of methanesulfonamides using various amine precursors. Additionally, the mixture of methanesulfonic anhydride and dimethyl sulfoxide can be used as an oxidizing agent for the oxidation of primary and secondary alcohols to aldehydes and ketones.

Application

Methanesulfonic anhydride can be used as an amine base to synthesize glycosyl mesylates in situ from the corresponding free hemiacetals under mild conditions.

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H314
• Precautionary Statements: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Hazard Classifications: Skin Corr. 1A
• Supplementary Hazards: EUH014
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves