357804

4′-Iodoacetophenone

≥97%

• Linear Formula: IC₆H₄COCH₃
• CAS Number: 13329-40-3
• Molecular Weight: 246.05
• EC Number: 236-372-8
• MDL number: MFCD00045320
• UNSPSC Code: 12352100
• PubChem Substance ID: 24861945
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: ≥97%
• mp: 82-84 °C (lit.)
• functional group: iodo; ketone
• SMILES string: CC(C1=CC=C(I)C=C1)=O
• InChI: 1S/C8H7IO/c1-6(10)7-2-4-8(9)5-3-7/h2-5H,1H3
• InChI key: JZJWCDQGIPQBAO-UHFFFAOYSA-N

Description

General description

Pd(0)-catalyzed cross coupling reaction of 4′-iodoacetophenone with siloxane has been reported. Heck-Mizoroki reactions of 4′-iodoacetophenone with styrene catalyzed by Pd nanoparticles in the flow reactor has been reported.

Application

4′-Iodoacetophenone may be used as substrate for the palladium-catalyzed coupling reactions. It may be used in the synthesis of quinoline-based potential anticancer agents.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves