385638

Di-(2-picolyl)amine

97%

• Synonym(s): Bis(2-pyridylmethyl)amine
• Empirical Formula (Hill Notation): C₁₂H₁₃N₃
• CAS Number: 1539-42-0
• Molecular Weight: 199.25
• EC Number: 216-266-8
• MDL number: MFCD00129044
• UNSPSC Code: 12352100
• PubChem Substance ID: 24864040
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 97%
• refractive index: n20/D 1.578 (lit.)
• bp: 139-141 °C/1 mmHg (lit.)
• solubility: water: soluble (partially miscible)(lit.)
• density: 1.107 g/mL at 25 °C (lit.)
• functional group: amine
• SMILES string: C(NCc1ccccn1)c2ccccn2
• InChI: 1S/C12H13N3/c1-3-7-14-11(5-1)9-13-10-12-6-2-4-8-15-12/h1-8,13H,9-10H2
• InChI key: KXZQYLBVMZGIKC-UHFFFAOYSA-N

Description

General description

Di-(2-picolyl)amine (DPA), a secondary amine containing two picolyl substituents, acts as a tridentate ligand due to its three donor nitrogen atoms. It is commonly used in coordination chemistry for the synthesis of binary, ternary, and binuclear complexes with various metal ions, including copper (Cu) and cadmium (Cd).

Application

Di-(2-picolyl)amine can be used as:

• A reactant to synthesize di(2-pyridylmethylamino)alkanoic esters using ω-iodoaliphatic carboxylic esters in the presence of triethylamine.
• A ligand to synthesize iron complexes of di-(2-picolyl)amine by treating with iron trichloride, which can be used to catalyze the direct hydroxylation of benzene to phenol.
• A reagent for the protection of carboxylic acids as carboxamides of bispicolylamine.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves