402516

1H-Pyrazole-1-carboxamidine hydrochloride

99%

• Synonym(s): 1-Amidinopyrazole hydrochloride, Praxadine
• Empirical Formula (Hill Notation): C₄H₆N₄ · HCl
• CAS Number: 4023-02-3
• Molecular Weight: 146.58
• Beilstein: 5448758
• EC Number: 429-520-1
• MDL number: MFCD00210087
• UNSPSC Code: 12352100
• PubChem Substance ID: 24865095
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: 99%
• form: powder
• mp: 167-170 °C (lit.)
• functional group: amine
• SMILES string: Cl[H].NC(=N)n1cccn1
• InChI: 1S/C4H6N4.ClH/c5-4(6)8-3-1-2-7-8;/h1-3H,(H3,5,6);1H
• InChI key: RBZRMBCLZMEYEH-UHFFFAOYSA-N

Description

General description

1H-Pyrazole-1-carboxamidine hydrochloride, a pyrazole derivative, is a heterocyclic compound. It is widely used in drug syntheses studies. Pyrazole ring forms the main core of various nonsteroidal anti-inflammatory drugs (NSAIDs) and antihypertensive drugs.

Application

1H-Pyrazole-1-carboxamidine hydrochloride may be used in the following studies:

• Preparation of guanidylated hollow fiber membranes.
• Guanylation of amines and in peptide synthesis.
• Synthesis of bis-guanidinium-cholesterol derivatives.

Safety Information

• Pictograms: GHS08,GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H302,H317,H318,H373,H412
• Precautionary Statements: P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P314
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves