438537

2-Amino-5-phenyl-1,3,4-thiadiazole

96%

• Empirical Formula (Hill Notation): C₈H₇N₃S
• CAS Number: 2002-03-1
• Molecular Weight: 177.23
• MDL number: MFCD00205278
• UNSPSC Code: 12352100
• PubChem Substance ID: 24867459
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 96%
• form: solid
• mp: 223-227 °C (lit.)
• functional group: phenyl
• SMILES string: Nc1nnc(s1)-c2ccccc2
• InChI: 1S/C8H7N3S/c9-8-11-10-7(12-8)6-4-2-1-3-5-6/h1-5H,(H2,9,11)
• InChI key: UHZHEOAEJRHUBW-UHFFFAOYSA-N

Description

General description

2-Amino-5-phenyl-1,3,4-thiadiazole on condensation with benzaldehyde (SPT), 4-nitrobenzaldehyde (SNT), 4-methoxybenzaldehyde (SMT), 2-hydroxybenzaldehyde (SSTH) or 2-hydroxyacetophenone affords Schiff′s bases. Its molecular geometry and vibrational frequencies have been evaluated using the Hartree-Fock and density functional method (B3LYP). 2-Amino-5-phenyl-1,3,4-thiadiazole has been reported to inhibit the corrosion of mild steel in 0.5M H₂SO₄ and 1.0M HCl. Corrosion inhibition has been examined using potentiodynamic polarization and electrochemical impedance spectroscopy (EIS).

Application

2-Amino-5-phenyl-1,3,4-thiadiazole may be used for the synthesis of 1,3,4-thiadiazole derivatives.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves