569313

1-Bromo-3,5-dimethoxybenzene

97%

• Synonym(s): 3,5-Dimethoxy-1-bromobenzene, 3,5-Dimethoxybromobenzene, 3,5-Dimethoxyphenyl bromide, 5-Bromo-1,3-dimethoxybenzene
• Linear Formula: BrC₆H₃(OCH₃)₂
• CAS Number: 20469-65-2
• Molecular Weight: 217.06
• MDL number: MFCD06200685
• UNSPSC Code: 12352100
• PubChem Substance ID: 24880494
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 97%
• form: solid
• mp: 62-66 °C (lit.)
• functional group: bromo
• SMILES string: COc1cc(Br)cc(OC)c1
• InChI: 1S/C8H9BrO2/c1-10-7-3-6(9)4-8(5-7)11-2/h3-5H,1-2H3
• InChI key: KRWRFIMBWRVMKE-UHFFFAOYSA-N

Description

General description

1-Bromo-3,5-dimethoxybenzene can be synthesized by using 1,3-dimethoxybenzene via iridium-catalyzed arene borylation.

Application

1-Bromo-3,5-dimethoxybenzene may be used to synthesize the following:

• bis-[di-(3,5-dimethoxyphenyl)methylcyclopentadienyl]titanium(IV)dichloride,{η⁵ - C₅H₄-CH-[C₆H₄-(OCH₃)₂]₂)₂TiCl₂ which can be used as an anti-cancer drug and is obtained via a multistep reaction process
• 5-bromo-benzene-1,3-diol via demethylation with boron tribromide(BBr₃)
• 1-bromo-3,5-dimethoxy-2-nitrobenzene via nitration reaction

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves