641375

4-Fluorophthalic anhydride

97%

• Empirical Formula (Hill Notation): C₈H₃FO₃
• CAS Number: 319-03-9
• Molecular Weight: 166.11
• MDL number: MFCD00191363
• UNSPSC Code: 12352100
• PubChem Substance ID: 24883115
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: 97%
• form: solid
• mp: 75-79 °C (lit.)
• functional group: anhydride; ester; fluoro
• SMILES string: Fc1ccc2C(=O)OC(=O)c2c1
• InChI: 1S/C8H3FO3/c9-4-1-2-5-6(3-4)8(11)12-7(5)10/h1-3H
• InChI key: XVMKZAAFVWXIII-UHFFFAOYSA-N

Description

General description

4-Fluorophthalic anhydride is a fluorinated building block commonly used in chemical synthesis for the preparation of polyimide, pesticides, herbicides, and fungicides. It can be synthesized by treating 4-chlorophthalic anhydride with potassium fluoride.

Application

4-Fluorophthalic anhydride can be used as a reactant to prepare:

• 4-amino substituted phthalimides applicable as potential fluorescent probes and fluorescent bioactive compounds.
• 4,4′-bis(4-fluorophthalimido)diphenyl ether monomer, which is used in the synthesis of cardo polymers via nucleophilic substitution polymerization reaction.
• Asymmetric polyimides by a solution polycondensation reaction.

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H301,H315,H319,H335
• Precautionary Statements: P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves