713783

O,O′-Bis[2-(N-Succinimidyl-succinylamino)ethyl]polyethylene glycol

2,000

• Synonym(s): Polyethylene glycol, α,ω-Bis-NHS-PEG, Di(N-succinimidyl) PEG-diacid, PEG-bis(N-succinimidyl succinate)
• CAS Number: 186020-53-1
• MDL number: MFCD03792507
• UNSPSC Code: 12162002
• NACRES: NA.22

Properties

• Quality Level: 100
• form: powder
• mol wt: average M_n 2,000
• reaction suitability: reagent type: cross-linking reagent
• Ω-end: NHS ester
• α-end: NHS ester
• storage temp.: −20°C

Description

General description

O,O′-Bis[2-(N-Succinimidyl-succinylamino)ethyl]polyethylene glycol (NHS-PEG-NHS) is a cross-linking reagent.

Application

O,O′-Bis[2-(N-Succinimidyl-succinylamino)ethyl]polyethylene glycol (NHS-PEG-NHS) is suitable reagent used in the covalent conjugation of peanut agglutinin and anticarcinoembryonic antigen antibodies (αCEA) tumor-targeting ligands to near-infrared (NIR)fluorescent superparamagnetic iron oxide (IO)- human serum albumin (HSA) nanoparticles. It is suitable reagent used in the synthesis of novel series of mesoporous silica nanoparticles with different pore sizes, useful for high loading and controlled release of short oligonucleotides.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves