779776

Methyl-β-cyclodextrin

Wacker Chemie AG, ≥95.0% cyclodextrin basis (calculated)

• Synonym(s): Cavasol^® W7 M, Methyl-beta-cyclodextrin
• CAS Number: 128446-36-6
• MDL number: MFCD00066764
• UNSPSC Code: 12352201
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: ≥95.0% cyclodextrin basis (calculated)
• form: powder
• manufacturer/tradename: Wacker Chemie AG
• extent of labeling: 1.6-1.9 molar substitution
• impurities: ≤0.2% unsubstituted cyclodextrin; ≤0.2% volatile organics; ≤2% chloride
• loss: ≤7.0% loss on drying
• mp: 180-182 °C (lit.)
• SMILES string: O1C2OC(C(OC3OC(C(OC4OC(C(OC5OC(C(OC6OC(C(OC7OC(C(OC8OC(C1C(C8OC)O)COC)C(C7OC)O)COC)C(C6OC)O)COC)C(C5OC)O)COC)C(C4OC)O)COC)C(C3OC)O)COC)C(C2OC)O)COC
• InChI: 1S/C56H98O35/c1-64-15-22-36-29(57)43(71-8)50(78-22)86-37-23(16-65-2)80-52(45(73-10)30(37)58)88-39-25(18-67-4)82-54(47(75-12)32(39)60)90-41-27(20-69-6)84-56(49(77-14)34(41)62)91-42-28(21-70-7)83-55(48(76-13)35(42)63)89-40-26(19-68-5)81-53(46(74-11)33(40)61)87-38-24(17-66-3)79-51(85-36)44(72-9)31(38)59/h22-63H,15-21H2,1-14H3
• InChI key: QGKBSGBYSPTPKJ-UHFFFAOYSA-N

Description

Application

Methyl-β-cyclodextrin (M-β-CD) can be used as a reactant to prepare ternary inclusion complex of diclofenac (DCF) in the presence of monoethanolamine (MEA). This complex improves the percutaneous absorption of DCF in human skin. It can also be used to form an inclusion complex with olanzapine (OLP) to increase its solubility for efficient drug delivery.

Other Notes

For R&D Use

Legal Information

Cavasol is a registered trademark of Wacker Chemie AG

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): 368.6 °F
• Flash Point(C): 187 °C