856525

2-Methyl-1,2-di-3-pyridyl-1-propanone

96%

• Synonym(s): Metyrapone, Su-4885
• Empirical Formula (Hill Notation): C₁₄H₁₄N₂O
• CAS Number: 54-36-4
• Molecular Weight: 226.27
• Beilstein: 163023
• EC Number: 200-206-2
• MDL number: MFCD00006397
• UNSPSC Code: 12352100
• PubChem Substance ID: 24888424
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 96%
• form: powder
• mp: 52-55 °C (lit.)
• functional group: ketone
• SMILES string: CC(C)(c1cccnc1)C(=O)c2cccnc2
• InChI: 1S/C14H14N2O/c1-14(2,12-6-4-8-16-10-12)13(17)11-5-3-7-15-9-11/h3-10H,1-2H3
• InChI key: FJLBFSROUSIWMA-UHFFFAOYSA-N

Description

Application

2-Methyl-1,2-di-3-pyridyl-1-propanone inhibits the biosynthesis of corticosterone by blocking the conversion of deoxycorticosterone to corticosterone.[1] It is widely used in adrenocortical-related clinical studies.[2][3]

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302,H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves