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85971

Sigma-Aldrich

Dipyrrolidino(N-succinimidyloxy)carbenium hexafluorophosphate

≥98.0% (CHN)

Synonym(s):

N,N,N′,N′-Bis(tetramethylene)-O-(N-succinimidyl)uronium hexafluorophosphate, O-(N-Succinimidyl)-N,N,N′,N′-bis(tetramethylene)uronium hexafluorophosphate, HSPyU

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About This Item

Empirical Formula (Hill Notation):
C13H20F6N3O3P
CAS Number:
Molecular Weight:
411.28
MDL number:
UNSPSC Code:
12352101
PubChem Substance ID:
NACRES:
NA.22
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Quality Level

Assay

≥98.0% (CHN)

form

solid

reaction suitability

reaction type: Coupling Reactions

mp

143-153 °C

solubility

acetonitrile: 0.1 g/mL, clear

application(s)

peptide synthesis

storage temp.

2-8°C

SMILES string

F[P-](F)(F)(F)(F)F.O=C1CCC(=O)N1O\C(N2CCCC2)=[N+]3\CCCC3

InChI

1S/C13H20N3O3.F6P/c17-11-5-6-12(18)16(11)19-13(14-7-1-2-8-14)15-9-3-4-10-15;1-7(2,3,4,5)6/h1-10H2;/q+1;-1

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1 of 4

This Item
2395512804T111060
HBTU ≥98.0% (T)

12804

HBTU

form

solid

form

solid

form

solid

form

powder or granules

assay

≥98.0% (CHN)

assay

≥97.5% (CHN)

assay

≥98.0% (T)

assay

≥99% (31P-NMR), ≥99.0% (reversed phase HPLC)

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

200

mp

143-153 °C

mp

153-156 °C

mp

200 °C (dec.) (lit.)

mp

-

solubility

acetonitrile: 0.1 g/mL, clear

solubility

-

solubility

acetonitrile: 0.1 g/mL, clear

solubility

-

Application

New, excellent and non-hygroscopic reagent for peptide coupling giving no cytotoxic reaction products
Reactant for synthesis of caspase sensitive gold nanoparticles

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Homan Kang et al.
Advanced materials (Deerfield Beach, Fla.), 32(6), e1905899-e1905899 (2019-12-20)
Advances in molecular imaging modalities have accelerated the diagnosis and treatment of human diseases. However, tumors less than 1 cm in size still remain difficult to localize by conventional means because of the difficulty in specific targeting/delivery to the tumor

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