858125C

18:1 Lyso PG

1-oleoyl-2-hydroxy-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt), chloroform

• Synonym(s): 1-oleoy-sn-glycero-3-phospho-(1′racglycerol) (sodium salt); PG(18:1(9Z)/0:0); 110714
• Empirical Formula (Hill Notation): C₂₄H₄₆O₉PNa
• CAS Number: 326495-24-3
• Molecular Weight: 532.58
• MDL number: MFCD00672604
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• Assay: >99% (LPG; may contain up to 10% of the 2-LPG isomer, TLC)
• form: liquid
• packaging: pkg of 5 × 4 mL (858125C-500mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 858125C
• concentration: 25 mg/mL (858125C-500mg)
• shipped in: dry ice
• storage temp.: −20°C

Description

General description

18:1 Lyso phosphoglycerol is a lyso-phospholipid detergent. Lyso-phospholipids are produced in γ-proteobacteria by lipoprotein acyltransferase activity. These lipids are found in minimal amount in normal bacterial membranes.

Application

18:1 Lyso PG has been used as a lipid standard in the optimization of the liquid chromatography-mass spectrometry (LC-MS) method conditions.

Biochem/physiol Actions

Lyso phosphoglycerol (Lyso PG) and acyl-CoA acts as a substrate for lysophosphatidylglycerol acyltransferase 1 (LPGAT1) to synthesize phosphoglycerol. Lyso-phospholipids are nonbilayer-forming lipids. Accumulation of lysophospholipids in bacterial membranes disrupt the membrane integrity due to its detergent- like physical property.

Packaging

5 mL Clear Glass Sealed Ampule (858125C-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• Precautionary Statements: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Target Organs: Central nervous system, Liver,Kidney
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable