870608H

4-HNE-dimethylacetal

Avanti Research^™ - A Croda Brand 870608H, hexane solution

• Synonym(s): (E)-4R-hydroxynonenal-dimethylacetal (Each vial contains 6.8mg which yields ~5.2mg 4-HNE after deprotection)
• Empirical Formula (Hill Notation): C₁₁H₂₂O₃
• CAS Number: 119009-01-7
• Molecular Weight: 202.29
• MDL number: MFCD22416914
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• form: hexane solution
• packaging: pkg of 1 × 1 mL (870608H-5mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 870608H
• concentration: 6.8 mg/mL (870608H-5mg)
• lipid type: phosphoglycerides; bioactive lipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: CCCCC[C@@H](O)/C=C/C(OC)OC
• InChI key: ATGIHMSJAARJTF-AAXQSMANSA-N

Description

General description

4-Hydroxynonenal (4-HNE or HNE) is an α,β-unsaturated hydroxyalkenal which is produced by lipid peroxidation in cells. 4-HNE has been hypothesized by several researchers to play a key role in cell signal transduction, in a variety of pathways from cell cycle events to cellular adhesion.
The dimethylacetal derivative is a more stable form of 4-HNE which is good for long term storage of the compound during use. It can be easily converted to 4-HNE in the presence of acid.

Packaging

2 mL Amber Glass Sealed Ampule (870608H-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Pictograms: GHS02,GHS08,GHS07,GHS09
• Signal Word: Danger
• Hazard Statements: H225,H304,H315,H336,H361f,H372,H411
• Precautionary Statements: P202 - P210 - P273 - P301 + P310 - P303 + P361 + P353 - P331
• Hazard Classifications: Aquatic Chronic 2 - Asp. Tox. 1 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Inhalation - STOT SE 3
• Target Organs: Central nervous system, Nervous system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): -14.8 °F - closed cup
• Flash Point(C): -26.0 °C - closed cup