880182P

DSPE-PEG(3400) Carboxylic acid

Avanti Polar Lipids

• Synonym(s): 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-3400] (sodium salt)
• Empirical Formula (Hill Notation): C₁₉₅H₃₈₅NNaO₈₇P
• Molecular Weight: 4190.06
• UNSPSC Code: 12352200

Properties

• biological source: synthetic
• Assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 25 mg (880182P-25MG)
• lipid type: polymerizable lipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [Na+].C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCCNC(=O)C\C=C\OOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOCCOOCC(O)=O)OC(=O)CCCCCCCCCCCCCCCCC

Description

General description

DSPE PEG(3400) COOH has numerous applications in biotechnology, pharmaceuticals, and drug delivery. The hydrophobic properties of DSPE enhance the encapsulation and collection of other hydrophobic drugs. When an activator such as EDC or HATU is present, the -COOH group can easily react with primary amines to form a stable amide bond. By altering the length of the PEG, it is possible to modify the micelle size, immunological safety, and drug release rate.

Application

Targeted drug delivery

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable