890705P

16:0-18:1 EPC (Cl Salt)

Avanti Research^™ - A Croda Brand 890705P, powder

• Synonym(s): 1-palmitoyl-2-oleoyl-sn-glycero-3-ethylphosphocholine (chloride salt)
• Empirical Formula (Hill Notation): C₄₄H₈₇NO₈PCl
• CAS Number: 328250-19-7
• Molecular Weight: 824.59
• MDL number: MFCD22495360
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• form: powder
• packaging: pkg of 1 × 10 mg (890705P-10mg); pkg of 1 × 25 mg (890705P-25mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 890705P
• application(s): advanced drug delivery
• lipid type: transfection; cationic lipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: O=P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)OCC.[Cl-]
• InChI: 1S/C44H87NO8P.ClH/c1-7-10-12-14-16-18-20-22-23-25-27-29-31-33-35-37-44(47)53-42(41-52-54(48,50-9-3)51-39-38-45(4,5)6)40-49-43(46)36-34-32-30-28-26-24-21-19-17-15-13-11-8-2;/h22-23,42H,7-21,24-41H2,1-6H3;1H/q+1;/p-1/b23-22-;/t42-,54?;/m1./s1
• InChI key: SXRDCCSKGWBZFF-ISBKSCLYSA-M

Description

General description

1-palmitoyl-2-oleoyl-sn-glycero-3-ethylphosphocholine (16:0-18:1 EPC) is cationic lipid containing an ethyl group attached to the phosphate moiety through an ester bond and has a choline headgroup.

Application

1-palmitoyl-2-oleoyl-sn-glycero-3-ethylphosphocholine (chloride salt) (16:0-18:1 EPC (Cl Salt)) might be used:

• as a cationic lipid to explore the change in organization and dynamics of a membrane-bound fluorescent probe in host membranes of varying charge
• in the preparation of small unilamellar cationic liposomes
• in a novel albumin-associated lipoplex formulation to evaluate the antitumoral efficacy of immuno-gene therapy and “suicide” gene therapy

Biochem/physiol Actions

1-palmitoyl-2-oleoyl-sn-glycero-3-ethylphosphocholine (16:0-18:1 EPC) is a potential transfection agent, which is also similar to the natural lipids.

Packaging

5 mL Clear Glass Sealed Ampule (890705P-10mg)

5 mL Clear Glass Sealed Ampule (890705P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids