LM1906

17:0-20:4 PI(3,4,5)P3

Avanti Research^™ - A Croda Brand LM1906, powder

• Synonym(s): 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′,5′-trisphosphate) (ammonium salt)
• Empirical Formula (Hill Notation): C₄₆H₉₆N₄O₂₂P₄
• CAS Number: 1246304-72-2
• Molecular Weight: 1181.16
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• form: powder
• manufacturer/tradename: Avanti Research^™ - A Croda Brand LM1906
• packaging: 1 ea of 1 × (with stopper and crimp cap (LM1906-1EA))
• application(s): lipidomics; metabolomics
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](OP([O-])(O)=O)[C@H](OP([O-])(O)=O)[C@@H](OP(O)([O-])=O)[C@H]1O)=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCC)=O.[NH4+].[NH4+].[NH4+].[NH4+]
• InChI: 1S/C46H84O22P4.4H3N/c1-3-5-7-9-11-13-15-17-19-20-21-23-25-27-29-31-33-35-40(48)64-38(36-62-39(47)34-32-30-28-26-24-22-18-16-14-12-10-8-6-4-2)37-63-72(60,61)68-43-41(49)44(65-69(51,52)53)46(67-71(57,58)59)45(42(43)50)66-70(54,55)56;;;;/h11,13,17,19,21,23,2
• InChI key: FSWQCDGXUXSIRI-VHLOILQVSA-N

Description

General description

Phosphatidylinositol-3,4,5-triphosphate (PI(3,4,5)P3) is localized to the plasma membrane, intracellular sites and the nucleus.

Application

17:0-20:4 PI(3,4,5)P3 or 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′,5′-trisphosphate) has been used:

• as a lipid standard in ultra-performance liquid chromatography-tandem mass spectrometry (UPLC/MS)
• as an internal standard in lipid extraction from Drosophila larval tissues
• as an internal standard in liquid chromatography tandem mass spectroscopic (LC-MS/MS) analysis of methylated phosphatidylinositol phosphates (PIPs)

Biochem/physiol Actions

Phosphatidylinositol-3,4,5-triphosphate (PI(3,4,5)P3) is involved in protein activation. It is a critical signaling molecule for several cellular processes and acts as a secondary messenger. PI(3,4,5)P3 is also implicated in human pathogenesis.

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (LM1906-1EA)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids