407709

Insulin, Zinc, Human, Recombinant, P. pastoris

• Synonym(s): Insulin, Zinc, Human, Recombinant, P. pastoris
• CAS Number: 11061-68-0
• MDL number: MFCD00131380
• UNSPSC Code: 12352202
• NACRES: NA.77
• biological source: yeast (Pichia pastoris)
• form: solid

Properties

• biological source: yeast (Pichia pastoris)
• Quality Level: 200
• description: Merck USA index - 14, 4980
• sterility: non-sterile
• Assay: ≥95—105%
• form: solid
• specific activity: ≥25 IU/mg (dry basis)
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• impurities: <10 EU/mg Endotoxin (EU/mg protein)
• color: white to off-white
• solubility: 0.01 M HCl: soluble
• shipped in: wet ice
• storage temp.: −20°C
• InChI key: PBGKTOXHQIOBKM-FHFVDXKLSA-N

Description

General description

Recombinant, human insulin (zinc) expressed in P. pastoris. Peptide anabolic hormone produced by pancreatic β-cells. Increases the synthesis of protein, fat, glycogen, and substrate oxidation in mitochondria. Interacts with membrane insulin receptor to cause its biological actions.

Warning

Toxicity: Standard Handling (A)

Preparation Note

Insulin is practically insoluble from pH 4.5-7.0.

Reconstitution

Following reconstitution store in the refrigerator (4°C). Stock solutions are stable for up to 6 weeks at 4°C.

Other Notes

Mohan, C., et al. 1989. Curr. Topics Cell. Reg.30, 105.
Johnson, I.S. 1983. Science219, 632.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: nwg