6.18607

Methanol

for chromatography, LiChrosolv^®

• Synonym(s): Methanol, Methyl alcohol
• Linear Formula: CH₃OH
• CAS Number: 67-56-1
• Molecular Weight: 32.04
• Beilstein: 1098229
• MDL number: MFCD00004595
• UNSPSC Code: 12191601

Properties

• grade: for chromatography
• Quality Level: 100
• vapor density: 1.11 (vs air)
• vapor pressure: 410 mmHg ( 50 °C); 97.68 mmHg ( 20 °C)
• product line: LiChrosolv^®
• autoignition temp.: 725 °F
• expl. lim.: 36 %
• refractive index: n20/D 1.329 (lit.)
• bp: 64.7 °C (lit.)
• mp: −98 °C (lit.)
• density: 0.791 g/mL at 25 °C (lit.)
• suitability: suitable for chromatography
• SMILES string: CO
• InChI: 1S/CH4O/c1-2/h2H,1H3
• InChI key: OKKJLVBELUTLKV-UHFFFAOYSA-N

Description

General description

Methanolis a high-purity solvent specifically designed for chromatographicapplications. It is used as a mobile phase component in high-performance liquidchromatography (HPLC), gas chromatography (GC), and thin-layer chromatography(TLC).

Application

Methanolcan be used as a derivatization solvent to form the methylated derivatives oftopiramate that can be analyzed using gas chromatography-mass spectrometry(GC-MS) for qualitative and quantitative determination of topiramate in serumsamples.

Legal Information

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225,H301 + H311 + H331,H370
• Precautionary Statements: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Target Organs: Eyes,Central nervous system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 49.5 °F - closed cup
• Flash Point(C): 9.7 °C - closed cup