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8.14727

Sigma-Aldrich

Brij® 58

for synthesis

Synonym(s):

Brij® 58, Polyoxyethylene (20) cetylether, Polyethyleneglycol (20) cetylether

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1 ML
CA$198.00

CA$198.00


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1 ML
CA$198.00

About This Item

Linear Formula:
HO-(CH2CH2O)n-(CH2)15-CH3
CAS Number:
MDL number:
UNSPSC Code:
12352104
EC Index Number:
500-014-1
NACRES:
NA.22

CA$198.00


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Quality Level

form

solid

potency

2500 mg/kg LD50, oral (Rat)

mp

38-42 °C

transition temp

flash point >149 °C

storage temp.

2-30°C

SMILES string

O(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCCCCCCCCCCCCCCC)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

InChI

1S/C56H114O21/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17-58-19-21-60-23-25-62-27-29-64-31-33-66-35-37-68-39-41-70-43-45-72-47-49-74-51-53-76-55-56-77-54-52-75-50-48-73-46-44-71-42-40-69-38-36-67-34-32-65-30-28-63-26-24-61-22-20-59-18-16-57/h57H,2-56H2,1H3

InChI key

NLMKTBGFQGKQEV-UHFFFAOYSA-N

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This Item
B7782B7407B3533
manufacturer/tradename

Nalgene® 2002-0004

manufacturer/tradename

Nalgene® 2002-0008

manufacturer/tradename

Nalgene® 2002-0001

manufacturer/tradename

Nalgene® 2002-0016

feature

with cap

feature

with cap

feature

with cap

feature

with cap

material

polypropylene cap, round bottle, polypropylene screw closure, translucent high-density polyethylene

material

polypropylene cap, polypropylene screw closure, round bottle, translucent high-density polyethylene

material

polypropylene cap, polypropylene screw closure, round bottle, translucent high-density polyethylene

material

polypropylene cap, polypropylene screw closure, round bottle, translucent high-density polyethylene

capacity

125 mL

capacity

250 mL

capacity

30 mL

capacity

500 mL

packaging

pack of 12 ea

packaging

pack of 12 ea

packaging

pack of 12 ea

packaging

pack of 12 ea

joint

Joints threaded neck (24)

joint

Joints threaded neck (24)

joint

Joints threaded neck (20)

joint

Joints threaded neck (28)

Application

  • Potential Activity of Micafungin and Amphotericin B Co-Encapsulated in Nanoemulsion against Systemic Candida auris Infection in a Mice Model.: This study investigates the use of Brij® 58 in formulating a nanoemulsion to enhance the efficacy of micafungin and amphotericin B against systemic Candida auris infections in mice. The results suggest significant improvements in drug delivery and antifungal activity (Marena et al., 2024).
  • Encapsulation of Pure Water-Stable Perovskite Nanocrystals (PNCs) into Biological Environment-Stable PNCs for Cell Imaging.: This research highlights the role of Brij® 58 in stabilizing perovskite nanocrystals, enhancing their stability and applicability in biological environments for cell imaging purposes (Zheng et al., 2024).
  • Improving Drug Delivery on Candida Albicans Using Geraniol Nanoemulsion.: This paper discusses the use of Brij® 58 in geraniol nanoemulsions to enhance drug delivery against Candida albicans, showing improved antifungal effectiveness and stability (Silva Pontes et al., 2023).
  • Combined Effect of Shaking Orbit and Vial Orientation on the Agitation-Induced Aggregation of Proteins.: Brij® 58 is utilized in this study to prevent protein aggregation in pharmaceutical formulations during agitation, highlighting its importance in maintaining protein stability (Dasnoy et al., 2024).

Analysis Note

Hydroxyl value: 45 - 60
Water (K. F.): ≤ 3.0 %
Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt.

Legal Information

Brij is a registered trademark of Croda International PLC

Pictograms

Environment

Hazard Statements

Precautionary Statements

Hazard Classifications

Aquatic Chronic 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

302.0 °F - closed cup

Flash Point(C)

150 °C - closed cup


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