67028

Methylglyoxal solution

technical, ~40% in H₂O

• Synonym(s): Acetylformaldehyde, Pyruvaldehyde, Pyruvic aldehyde
• Linear Formula: CH₃COCHO
• CAS Number: 78-98-8
• Molecular Weight: 72.06
• Beilstein: 906750
• MDL number: MFCD00006960
• UNSPSC Code: 12352100
• PubChem Substance ID: 329760261
• NACRES: NA.22

Properties

• grade: technical
• Quality Level: 200
• concentration: ~40% in H₂O
• density: 1.19 g/mL at 20 °C
• functional group: aldehyde; ketone
• storage temp.: 2-8°C
• SMILES string: [H]C(=O)C(C)=O
• InChI: 1S/C3H4O2/c1-3(5)2-4/h2H,1H3
• InChI key: AIJULSRZWUXGPQ-UHFFFAOYSA-N

Description

General description

Methylglyoxal is a toxic endogenous by-product of glycolysis. It is a reactive dicarbonyl compound that promotes non-enzymatic glycation of proteins to yield irreversible advanced glycated end products, leading to the cross-linking or degradation of proteins.

Application

Methylglyoxal solution is used in cytotoxic studies.

Safety Information

• Pictograms: GHS08,GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H290,H317,H318,H341
• Precautionary Statements: P202 - P234 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Eye Dam. 1 - Met. Corr. 1 - Muta. 2 - Skin Sens. 1
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves