SMB00971

4-Ethylphenol sodium sulfate

• Synonym(s): 4-Ethylphenyl sulfate sodium salt
• Empirical Formula (Hill Notation): C₈H₉NaO₄S
• Molecular Weight: 224.21
• UNSPSC Code: 51171629
• NACRES: NA.77
• form: solid

Properties

• Assay: ≥98.0% (HPLC)
• Quality Level: 200
• form: solid
• storage temp.: −20°C

Description

General description

4-Ethylphenol sodium sulfate is the sodium salt of 4-Ethylphenyl sulfate (4EPS). 4-Ethylphenyl sulfate is a gut microbial metabolite derived from tyrosine, which is converted into 4-ethylphenol and subsequently sulfated in the liver. Upregulated urine 4EPS levels are found among rats prone to insulin resistance and obesity. Increased plasma 4EPS was reported in a murine model of autism, and mice treated with 4EPS displayed anxiety-like behaviours. Higher levels of 4-ethylphenylsulfate were also found in plasma, liver, heart and kidneys in a rat model of chronic kidney disease. 4EPS is a component of the urine of male rats, and both 4-ethylphenyl sulfate and 4-ethylphenol are thought to participate in pheromonal communication. p-Cresol-sulfate and 4-ethylphenyl sulfate are thought to derive from tyrosine and have similar bioactivities, however their enzymatic production may differ.

Application

Metabolomics research
Microbiome research

Other Notes

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Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable