A5356
N-Me-Abz-Amyloid β/A4 Protein Precursor770 (708-715)-Lys(Dnp)-D-Arg-D-Arg-D-Arg amide trifluoroacetate salt
≥96% (HPLC), lyophilized powder
Synonym(s):
N-Me-Abz-Amyloid β-Protein (37-44)-Lys(Dnp)-D-Arg-D-Arg-D-Arg amide trifluoroacetate salt
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About This Item
Empirical Formula (Hill Notation):
C70H116N26O18 · xC2HF3O2
Molecular Weight:
1609.83 (free base basis)
UNSPSC Code:
12352200
NACRES:
NA.32
Quality Level
Assay
≥96% (HPLC)
form
lyophilized powder
composition
Peptide content, 92% HPLC
solubility
H2O: >1 mg/mL
shipped in
dry ice
storage temp.
−20°C
Amino Acid Sequence
N-Me-Abz-Gly-Gly-Val-Val-Ile-Ala-Thr-Val-Lys(Dnp)-D-Arg-D-Arg-D-Arg-NH2
Biochem/physiol Actions
A novel intramolecularly quenched fluorescent, presenilin-dependent substrate for assaying γ -secretase activity. It has been used for partial purification and characterization of γ-secretase from post-mortem human brain.
An intramolecularly quenched, fluorescent γ-secretase substrate.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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