B169

BRL 37344 sodium salt hydrate

solid

• Synonym(s): (±)-(R*,R*)-[4-[2-[[2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]phenoxy]acetic acid sodium hydrate, BRL 37344A
• Empirical Formula (Hill Notation): C₁₉H₂₁ClNNaO₄ · xH₂O
• CAS Number: 127299-93-8
• Molecular Weight: 385.82 (anhydrous basis)
• MDL number: MFCD09971030
• UNSPSC Code: 12352200
• PubChem Substance ID: 24277764
• NACRES: NA.77

Properties

• Assay: ≥98% (HPLC)
• Quality Level: 100
• form: solid
• color: white
• solubility: DMSO: 18 mg/mL, clear (warmed)
• SMILES string: O.[Na+].C[C@H](Cc1ccc(OCC([O-])=O)cc1)NC[C@H](O)c2cccc(Cl)c2
• InChI: 1S/C19H22ClNO4.Na.H2O/c1-13(21-11-18(22)15-3-2-4-16(20)10-15)9-14-5-7-17(8-6-14)25-12-19(23)24;;/h2-8,10,13,18,21-22H,9,11-12H2,1H3,(H,23,24);;1H2/q;+1;/p-1/t13-,18+;;/m1../s1
• InChI key: YTPAKDODIXRQTF-BNTHFPBMSA-M
• Gene Information: human ... ADRB3(155)

Description

Biochem/physiol Actions

BRL 37344 is a selective β₃-adrenoceptor agonist.

BRL 37344 is a selective β₃-adrenoceptor agonist. Studies support the hypothesis that there are peripheral β₃ adrenergic receptors that can reduce food intake and that central β₂ or β₃ adrenergic receptors mediate the peripheral effects of the β₃ agonist.

Features and Benefits

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Caution

Hygroscopic; store desiccated.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves