B2517

6-Biopterin

≥97%

• Synonym(s): (1’R,2’S)-Biopterin, 2-Amino-4-hydroxy-6-(1,2-dihydroxypropyl)pteridine, L-erythro-6-(1,2-Dihydroxypropyl)pterin
• Empirical Formula (Hill Notation): C₉H₁₁N₅O₃
• CAS Number: 22150-76-1
• Molecular Weight: 237.22
• Beilstein: 87860
• EC Number: 244-807-8
• MDL number: MFCD00036787
• UNSPSC Code: 41106305
• PubChem Substance ID: 24891654
• NACRES: NA.51

Properties

• biological source: synthetic
• Quality Level: 200
• Assay: ≥97%
• form: powder
• solubility: 1 M NaOH: soluble-10 mg/mL, clear, colorless to light greenish-yellow
• storage temp.: 2-8°C
• SMILES string: C[C@H](O)[C@H](O)c1cnc2NC(N)=NC(=O)c2n1
• InChI: 1S/C9H11N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h2-3,6,15-16H,1H3,(H3,10,11,13,14,17)/t3-,6-/m0/s1
• InChI key: LHQIJBMDNUYRAM-DZSWIPIPSA-N

Description

Application

6-Biopterin is an oxidation product from the melanogenesis regulating cofactor (6R)5,6,7,8 tetrahydrobiopterin (6-BH4). In vitro, 6-Biopterin is cytotoxic to melanocytes. However, in vivo, 6-Biopterin is rapidly and sequentially reduced back to 6-GH4 via q-BH2. Recent studies suggest that 6-Biopterin among other pteridines may be a useful non-invasive biomarker for cancer.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves