C9819

Chondroitin sulfate A sodium salt from bovine trachea

lyophilized powder, BioReagent, suitable for cell culture

• Synonym(s): Alternating Copoly β-glucuronic acid-(1→3)-N-acetyl-β-galactosamine-4-sulfate-(1→4)
• CAS Number: 39455-18-0
• MDL number: MFCD00130792
• UNSPSC Code: 12352202
• NACRES: NA.75

Properties

• biological source: bovine trachea
• Quality Level: 200
• product line: BioReagent
• form: lyophilized powder
• packaging: poly bottle of 25 g; poly bottle of 5 g
• technique(s): cell culture | mammalian: suitable
• surface coverage: 20‑2000 μg/cm²
• shipped in: ambient
• storage temp.: 2-8°C

Description

Application

Chondroitin appears to play a regulatory role for chondrocytes, neural cells, and some tumor cells. Chondroitin sulfate B is used to study ß peptide (1-42) cytotoxicity.

Biochem/physiol Actions

As a large, negatively charged, hydrophilic molecule that is too inflexible to fold into a compact globular structure, chondroitin sulfate molecules form porous hydrated gels, providing mechanical support to tissue and allowing rapid diffusion of water-soluble molecules and migration of cells.

Components

Chondroitin Sulfate A is an acidic mucopolysaccharide found in cartilage, skin, cornea, and umbilical cord. It is composed of alternating N-acetylgalactosamine, D-glucuronic acid, and sulfate residues in equimolar quantities where carbon 4 of the N-acetylgalactosamines is sulfated.

Caution

Store this product at 2-8°C.

Preparation Note

This product is soluble in water at 100 mg/mL.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves