D3314

D-erythro-Dihydrosphingosine

≥98%

• Synonym(s): Sphinganine
• Empirical Formula (Hill Notation): C₁₈H₃₉NO₂
• CAS Number: 764-22-7
• Molecular Weight: 301.51
• MDL number: MFCD07371371
• UNSPSC Code: 12352211
• PubChem Substance ID: 24893744
• NACRES: NA.77

Properties

• biological source: synthetic (organic)
• Quality Level: 200
• Assay: ≥98%
• form: solid
• color: white
• solubility: DMSO: 25 mg/mL (warm); ethanol: 25 mg/mL (warm)
• lipid type: sphingolipids
• storage temp.: −20°C
• SMILES string: OC[C@@](N)([H])[C@]([H])(O)CCCCCCCCCCCCCCC
• InChI: 1S/C18H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h17-18,20-21H,2-16,19H2,1H3/t17-,18+/m0/s1
• InChI key: OTKJDMGTUTTYMP-ZWKOTPCHSA-N

Description

Application

D-erythro-Dihydrosphingosine has been used:

• as a standard lipid in quantification assay
• in kinetics assay
• to determine serine palmitoyl transferase activity

Biochem/physiol Actions

D-erythro-Dihydrosphingosine is a natural stereoisomer. The levels of dihydrosphingosine (DHS) is increased during unfolded protein response (UPR).

Biosynthetic precursor to sphingosine; inhibits protein kinase C.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves