E1768

5,8,11,14-Eicosatetraynoic acid

≥97%

• Synonym(s): ETYA, Octadehydroarachidonic acid
• Empirical Formula (Hill Notation): C₂₀H₂₄O₂
• CAS Number: 1191-85-1
• Molecular Weight: 296.40
• Beilstein: 1798411
• MDL number: MFCD00036967
• UNSPSC Code: 12352106
• PubChem Substance ID: 24894432
• NACRES: NA.77

Properties

• biological source: synthetic (organic)
• Quality Level: 200
• Assay: ≥97%
• form: powder
• mp: 78-80 °C
• solubility: ethanol: 50 mg/mL, clear, colorless to yellow
• storage temp.: −20°C
• SMILES string: CCCCCC#CCC#CCC#CCC#CCCCC(O)=O
• InChI: 1S/C20H24O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h2-5,8,11,14,17-19H2,1H3,(H,21,22)
• InChI key: MGLDCXPLYOWQRP-UHFFFAOYSA-N
• Gene Information: human ... ALOX15(246)

Description

Biochem/physiol Actions

Eicosatetraynoic acid (ETYA) is a non-metabolizable analog of ω-6 arachidonic acid. ETYA is a strong activator of the human peroxisome proliferator-activated receptor α (PPARα). It acts as an inhibitor of lipoxygenases (LOX) and cyclooxygenases (COX).

Eicosatetraynoic acid is a lipoxygenase and cyclooxygenase inhibitor.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves