FD70S

Fluorescein isothiocyanate–dextran

average mol wt 60,000-76,000

• Synonym(s): FITC–Dextran
• CAS Number: 60842-46-8
• MDL number: MFCD00131092
• UNSPSC Code: 12352201
• NACRES: NA.25

Properties

• biological source: bacterial (Leuconostoc mesenteroides)
• Quality Level: 200
• conjugate: FITC conjugate
• form: powder
• mol wt: average mol wt 60,000-76,000
• extent of labeling: 0.003-0.020 mol FITC per mol glucose
• color: yellow to yellow-orange
• solubility: H₂O: 25 mg/mL, clear to slightly hazy, yellow-orange
• storage temp.: 2-8°C

Description

Application

Dextran labeled with fluorescein isothiocyanate for possible use in perfusion studies in animals.

FITC-dextran is used in cardiovascular, microcirculation, perfusion, cell monolayer and cell membrane permeability research as fluorescent flux tracer compound that supports the measurement of processes such as blood flow, membrane damage, vascular drainage and renal elimination. Small FITC-dextrans are also used to measure processes such as endocytosis and cell junction permeability. FITC-dextran 70 kDa (FD-70) may be used as a model compound for development of methods to deliver molecules into protoplasts and to study drug release from structures such as hydrogels and liposomes. FD-70 may be used in microvascular and cell monolayer permeability studies.

Linkage

Similar to FD-70, but produced by Sigma.

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves